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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Mal-PEG5-PFP ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked by a connector: one ligand targets an E3 ubiquitin ligase, while the other targets the specific protein. They leverage the intracellular ubiquitin-proteasome system for the targeted degradation of proteins[1]. |
Molecular Weight | 555.45 |
Formula | C23H26F5NO9 |
Cas No. | 1807512-46-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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